Drug Interactions-Important Points 1. Doctors must be careful in prescribing drugs with narrow therapeutic index, such as phenytoin, theophylline and digoxin, 2. Drugs which need proper dosage control, like hypoglycemics, antihypertensives and anticoagulants, need proper monitoring for drug interactions. 3. Old people and people with hepatic or renal impairment are potentially at risk, for adverse drug reactions. 4. Drug interaction causing agents include alcohol, tobacco, OTC drugs, NSAIDs and antacids. 5. Clinical importance of drug interactions depends on a variety of factors. 6. If there is less likelihood of an interaction with another member of a drug group, it is better to go for it. 7. When a drug interaction is suspected, careful monitoring should be done. 8. Dug information sources must be carefully studied and utilised for every given situation. Reference: 1. The Pharmaceutical Journal, (Vol 261), October 17, 1998, page 620. This blog does not contain plagiarised material.