Patient counselling for antibiotics: Penicillins

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Information for pharmacist:

  1. These medicines are best taken with a full glass of water on an empty stomach or as directed by the physician.
  2. Do not take acidic fruit juices like grape fruit juice or beverages within 1 hour of taking penicillin G, as it may reduce efficacy.
  3. For a chewable tablet form, the tablet should be chewed thoroughly and then swallowed.
  4. Advice patients on:
  • * Usage of medicine for the full course.
  • * Warn the patient against the use of anti diarrheal medication with these medicines without consultation of the physician.
  • * Suggest alternate methods of birth control other than oral contraceptives, as they contain estrogen which may not be compatible with some of the medicines of this class.

Dosing for drugs:

  • Ticarcillin
    • Injection
      • Adults, teenagers and children weighing more than 40 kg: 3 g injected into vein every 4 hours or 4 g injected every 6 hours
      • Children upto 40 kg: 33.3-75 mg/kg body weight injected into vein every 4-6 hours. .
  • Carbenicillin
    • Injection
      • Adults and teenagers: 50-83.3 mg/kg body weight injected into muscle or vein every 4 hours
      • Older infants and children: 16.7-75 mg/kg body weight injected into muscle or vein every 6 hours .
    • Tablets
      • Adults and teenagers: 500 mg-1 gevery 6 hours
      • Children: dose determined by doctor

Information for patient:

  1. The dose will be different for different individuals.
  2. Follow doctor's directions for dosage strictly.
  3. Change of dose must be done only after consultation with the doctor.
  4. The dosage regimen is different for different disease conditions.
  5. Take doses on time. If a dose is missed, take it as soon as possible, avoid double dosing.
  6. In case of diabetic patients, penicillins may give false results in urine sugar tests.
  7. Stop the medication and seek medical attention immediately if any of these problems arise:
  • * Fast or irregular breathing.
  • * Joint pains
  • * Mental depression
  • * Sudden fainting
  • * Puffiness of face
  • * Diarrhea and abdominal cramps
  • * Convulsions


1) Advice for the patient: Drug information in lay language; USP DI; 1995,15th edition; pg: 1302-1306 [access date: 16thSeptember, 2010]

2) [access date: 16th September, 2010]

3) [access date: 16th September, 2010]

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Niklesh Rao V's picture
Author: Niklesh Rao V


P.V.ABHIGNA's picture

Niklesh, Joint pains is due to what, I mean is it becoz of some deposition ? Regards,


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