Drug Advice: ALPRAZOLAM

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Information for the pharmacist:

1.Anti-anxiety agent.

2.It is important not to take more medication than the amount prescribed
because of habit forming potential.

3.It is important not to increase the dose of medication, if the given dose
is less effective alter a few weeks. Doctor should be consulted.

4.Missed dose: If a patient is on a scheduled dosing regimen, and misses
a dose, then,

If remembered within an hour so, the dose may be taken right away.
If remembered later than an hour, the dose should not be taken at all.
The dose should not be doubled.

Precautions while using this medicine:

1. Caution in taking alcohol or other CNS depressants during therapy.

2. Suspected overdose, getting emergency help at once.

3. Caution if drowsiness, dizziness, light headedness, or clumsiness or
unsteadiness occurs, especially m the elderly.

Information for the patient:

I Take the medicine about half an hour before you want to sleep, then go to bed.

2.Do not take drinks with caffeine before going to bed, as they may keep you awake.

3.Do not take more medicine than what is prescribed to you.

4.Maximum effectiveness of medication may not occur for 2 or 3 nights after initiating therapy.

5.Keep this medicine out of reach of children, overdose is especially dangerous in children.

6.Be careful if you have to get up in the night, as you may feel very sleepy. If you still feel drowsy in the morning do not drive.

7.You should not drink alcohol. Even during the day, while taking this medicine.

Reference:
1. Advice for the patient: Drug information in lay language; USP DI; 1995,15th edition; pg nos: 389-396.

2. http://www.rxlist.com/xanax-drug.htm [Accessed on 27th August 2010]

3. http://www.medicineonline.com/drugs/a/2981/Alprazolam-Tablets-USP-CIV.html [Accessed on 27th August 2010]

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About the Author

Niklesh Rao V's picture
Author: Niklesh Rao V

Comments

Prof. J. Vijaya Ratna's picture

Dear Niklesh You brought out the essentials of alprozalam, good. You must also start giving some popular brand names for each drug by consulting either CIMS or Drug Today. Vijaya Ratna
Niklesh Rao V's picture

I will definitely do that ma'am. Thank you for your valuable suggestions.

Regards, Niklesh Rao V

Amol Malpani's picture

Dear Nikhlesh, You wrote in your blog Clarify this line..... 'Do not take drinks with caffeine before going to bed, as they may keep you awake.' if patient is awake what happen, is it reduce the effect of drug? if yes, how? Regards,
Niklesh Rao V's picture

Dear sir, Alprazolam is a CNS depressant. It is indicated as a hypnotic and sedative. The main purpose of the drug is to relieve the patient of sleeplessness. If the patient takes caffeine, which is a CNS stimulant, it antagonizes the effect of Alprazolam and impedes its action. Thus, in essence causing the failure of the purpose of administering the drug.

Regards, Niklesh Rao V

P.V.ABHIGNA's picture

Niklesh, Good job and yes as madam mentioned above do keep a track of the brand names as doctors and common people are generally not aware of the chemical compositions. Regards,

ABHIGNA.P.V.

S.M. Habibur rahman's picture

Good piece of information
Niklesh Rao V's picture

Thank you for your comment sir.

Regards, Niklesh Rao V

TK Indira's picture

Good work done. Thanks for sharing.Posting such blogs really creates awareness among pharma professionals.

T.K. Indira. http://www.pharmainfo.net/tkindira

-- "Our greatest glory is not in never falling, but in rising every time we fall..." Team 'Char'minar.

Niklesh Rao V's picture

Thank you for your comment Indira.

Regards, Niklesh Rao V

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