Shortcuts for Pharmacology drugs - GPAT Notes

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 GPAT AND NIPER Study Notes

Short cuts for GPAT AND NIPER


Busulfan feature : ABCDEF
Alkylating agent
Bone marrow suppression
CML Indication
Dark skin(hyperpigmentation)
Endocrine insufficiency(adrenal)
Fibrosis


Drugs causing Torsades de Pointes:APACHE
Amiodarone
Procainamide
Arsenium
Cisapride
Haloperidol
Erythromycin


Morphine side effects :MORPHINE
Myosis
Out of it(sedation)
Respiratory depression
Pneumonia(aspiration)
Hypotension
Infrequency(constipation,urina
ry retention)
Nausea
Emesis


Aspirin side effects :ASPIRIN
Asthma
Salicylism
Peptic ulcer disease/phosphorylation-oxidat
ion uncoupling/platelet disaggregation
Intestinal blood loss
Reye's Syndrome
Idiosyncracy
Noise(tinnitus)


SSRIs side effects :SSRI
Seratonin syndrome
Stimulate CNS
Reproductive disfunction in male
Insomnia


Inhalation anesthetics : SHINE
Sevoflane
Halothane
Isoflurane
Nitrous oxide
Enflurane


Teratogenic drugs :"Win TERATogenic
Warfarin
Thalidomide
Epileptic drugs:Phenytoin,Valproate,Carb
amazepine
Retinoid
ACE inhibitor
Third element :Lithium


Gynaecomastia causing drugs:DISCOS
Digoxin
Isoniazid
Spironolactone
Cimetidine
Oestrogens
Stilboestrol


Methyldopa Side effects :METHYLDOPA
Mental retardation
Electrolyte imbalance
Tolerance
Headache/ Hepatotoxicity
psYcological upset
Lactation in female
Dry mouth
Oedema
Parkinsonism


Antirheumatic agents :CHAMP
Cyclophosphamide
Hydroxycloroquine and choloroquinine
Auranofin and other gold compounds
Methotrexate
Penicillamine


Phenytoin: adverse effects PHENYTOIN
P-450 interactions
Hirsutism
Enlarged gums
Nystagmus
Yellow-browning of skin
Teratogenicity
Osteomalacia
Interference with B12 metabolism (hence anemia)
Neuropathies: vertigo, ataxia, and headache


Sodium Valproate side effccts VALPROATE
Vomiting
Alopecia
Liver toxicity
Pancreatitis/ Pancytopenia
Retention of fats (weight gain)
Oedema (peripheral oedema)
Appetite increase
Tremor
Enzyme inducer (liver)


Amiodarone: action, side effects: 6 P's:
Prolongs action potential duration
Photosensitivity
Pigmentation of skin
Peripheral neuropathy
Pulmonary alveolitis and fibrosis
Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism


Antiparkinson Drugs :SALAD
Selegiline
Anticholinenergics (trihexyphenidyl, benzhexol, ophenadrine)
L-Dopa + peripheral decarboxylase inhibitor (carbidopa, benserazide)
Amantadine
Dopamine postsynaptic receptor agonists (bromocriptine, lisuride, pergolide)


Therapeutic Index Formula TILE
TI = LD / ED


Anti epeleptic drugs Dr.BHAISAB's New PC.
Deoxy barbiturates
Barbiturates
Hydantoin
Aliphatic carb acids
Iminostilbenes
Succinimides
BZD's
Newer drugs
Phenyltriazines
Cyclic gaba analogues


Adverse effects of Tetracyclines-KAPIL DEV
Kidney toxicity
Antianabolic effect
Phototoxicity
Liver toxicity
Diabetes insipidus


CAPTOPRIL Side effects CAPTOPRIL
Cough Angioedema
Agranulocystosis
Proteinuria/ Potassium excess
Taste changes
Orthostatic hypotension
Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose hypertension)
Renal failure (and renal artery stenosis contraindication)/ Rash
Indomethacin inhibition
Leukopenia/Liver toxicity


Lithium: side effects LITH
Leukocytosis
Insipidus [diabetes insipidus, tied to polyuria]
Tremor/ Teratogenesis
Hypothyroidism


Myocardial Infarction(MI): signs and symptoms PULSE
Persistent chest pains
Upset stomach
Lightheadedness
Shortness of breath
Excessive sweating


MI: basic management (Shortcut:BOOMAR)
Bed rest
Oxygen
Opiate
Monitor
Anticoagulate
Reduce clot size


Treatment of Heart Failure: ABCDE
ACE inhibitors
Beta-blockers
Calcium channel blockers
Diuretics
Endothelin-converting enzyme inhibitors


Essential Amino acids
Methionine
Threonine
Leucine
Isoleucine
Tryptophan
Valine
Lysine
Phenyl alanine

Source:Pharmagupshup.in

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About the Author

Charan Karumuri's picture
Author: Charan Karumuri

I am currently preparing for GPAT and would like to share GPAT related information through my blogs.

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Comments

Eswar GsnkRao's picture

Dear Charan,

Excellent Notes for GPAT Aspirants.

Keep posting such useful info for readers.

Here I would like to suggest you few things for complete professionality.

1) Make a habbit of giving reference for your data. JUST TO AVOID pLAGIARISM.

2) Add your own inputs in addition to obtained data from various sources.

Here are few links for your sake:

http://www.pharmainfo.net/tegkmurthy/blog/plagiarism

http://www.pharmainfo.net/rojarani/blog/attempt-make-plagiarism-practica...

Regards

ESWAR :-) 

Sirisha Pingali's picture

Sir, your comment is apt and yes it is quintessential to avoid plagiarism.

Wish to see many such informative blogs from you Charan!

Sirisha Pingali

http://www.pharmainfo.net/sirisha

Viswanadha Institute of Pharmaceutical Sciences.

www.vnips.edu.in

Charan Karumuri's picture

Its been a long time seeing u back on pharmainfo.net

Charan

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