A range of assay methods are used to detect viral contaminants in the raw materials and final finished products. It is obvious that a single viral assay cannot detect the entire viral types present in the sample. So how can we actually determine the viral contaminants. The strategy developed is simple. It mainly focuses on the possible viral contaminant of the source material being used. Also it does not include newly discovered or unknown viral contaminants. Current viral assays falls into 3 categories. 1. Immunoassays 2. Assays based on viral DNA probes
The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use which we simply refer as ICH is a distinct in getting together the various "regulatory authorities and pharmaceutical industry" of Japan, Europe and US to discuss about various scientific and technical requirements of drug registration.
PACEMAKER AND NONPACEMAKER CELLS -Heart has primarily two kinds of myocyte cells- Pacemaker cells (Those that can spontaneously initiate action potentials) and Nonpacemaker cells.
Aptamers are segments of DNA or RNA that congregate to form a 3D structure thereby allowing them to bind to a specific target. This binding is characterized by * High Specificity * High affinity- nanomolar to picomolar range- often resembles the binding of antibody and antigen.
Hello everyone, the topic I chose for this month is purely based on the two catchy words mentioned in the title, SHONIN and KYOKA. I was going through this book and suddenly I noticed a subheading DRUG REGISTRATION IN JAPAN. The Japanese constitutes the greatest consumers of pharmaceutical products "per capita" in the world.