Which drugs can exhibit teratogenic effects?

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P.V.ABHIGNA's picture

A teratogen is a agent that can disturb the development of an embryo or fetus. These agents halt pregnancy. Drugs acting as teratogens are: 1)ACE inhibitors captopril Enalopril Lisinopril benazepril 2)Antibiotics: Tetracyclin doxycycline streptomycin. 3)Anticoagulant-Warfarin 4)Anticonvulsant Phenytoin valproic acid 5)Antidepressant-lithium 6)Others-methotrexate, pencillamine, thiouracil, cocaine, DES etc REF:http://www.medterms.com/script/main/art.asp?articlekey=9334


Seema Meena's picture

ACE inhibitors (treats hypertension and congestive heart failure) (renal dysgenesis [abnormal or defective development of the kidneys], oligohydramnios sequence [deficiency of amniotic fluid during pregnancy], skull ossification defects) alcohol (go here) aminopterine (chemotherapy) and methotrexate (treats arthritis and rheumatic [us. bones and joints, etc.] conditions) (pregnancy loss, hydrocephalus [excess cerebrospinal fluid in the ventricles of the brain], low birth weight, dysmorphic facial features) androgens and high doses of nor-progesterones (steroid; contraceptive) (masculinization of external female genitalia) anticancer drugs (pregnancy loss, neural tube defects, hydrocephalus, growth retardation, cardiovascular malformations) antithyroid drugs (hypothyroidism, goiter) many more drugs are there in pharmacology which cause tertaogenicity ref http://www.catherineshafer.com/teratogens.html


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