What are the natural painkillers in brain?

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Ankur sood's picture

Answer: 
There are endogenous analgesic substances with peptide structure and morphine like action and were isolated from the mamalian brain pituitay, gastro intestinal track and spinal cord. a) Endorphins - beta-endorphins Derived from pro - opiomelanocortin Activate m receptors; b) Enkephalins - Two types :- met - ENK and leu - ENK Derived from Pro-enkephalin Activate m and d-receptors; c) Dynorphins - Two types :- DYN ( A and B) Activate k receptors. Derived from pro - dynorphin Reference http://www.discoveriesinmedicine.com/Com-En/Endorphin-and-Enkephalin.html With Regards Ankur Sood team GLORY

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