estrogen interaction with amoxicillin?

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Muhammad Aslam's picture

Answer: 
Estrogen is used as an oral contraceptive agent. When Estrogen is taken it is metabolized by liver and secreted into intestine where it is again converted into usable form (from its metabolites) with the help of intestinal flora. This leads to an increase level of estrogen in the blood but when Estrogen is taken with amoxicillin , Estrogen level decreases as the amoxicillin decreases the intestinal flora. So due to decrease of estrogen level ovulation & pregnancy can take place while you are on antobitics and contraceptives containing hormones like Estrogen at the same time.

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