What is nonsense mutation?

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kranthi kumar's picture

In nonsense mutation, some non functional proteins are produced. http://en.wikipedia.org/wiki/Nonsense_mutation
Amol Dhiaman's picture

In the nonsense mutation the new nucleotide changes a codon that specified an amino acid to one of the STOP codons (TAA, TAG, or TGA). Therefore, translation of the messenger RNA transcribed from this mutant gene will stop prematurely. The earlier in the gene that this occurs, the more truncated the protein product and the more likely that it will be unable to function. Reference: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/M/Mutations.html With Regards Amol Dhiman Team GLORY

Amol Dhiaman

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