What is margination?

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Amol Dhiaman's picture

Margination is the process in which free-flowing leukocytes exit the central blood stream, and initiate leukocyte and endothelial cell interactions by close mechanical contact. The underlying mechanisms of margination involve the interaction of leukocytes with erythrocytes flowing in the same microvessel, whereby deformed erythrocytes push leukocytes to a marginating position due to their smaller cross section and higher flow velocity. Reference: http://bme.virginia.edu/ley/margination.html With Regards Amol Dhiman Team GLORY

Amol Dhiaman

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