What is melanogenesis. By what it is stimulated?

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Melanogenesis is the production of melanin which is a cutaneous pigment. The most important positive stimulant of melanogenesis is the MC1 receptor with its ligands melanocortic peptides. MC1R activates the cyclic AMP (cAMP) response-element binding protein (CREB).

Referenec: http://www.genome.jp/dbget-bin/www_bget?pathway+hsa04916

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