Difference between induced and spontaneous mutations.

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Siva Mavuduru's picture

Answer: 
Spontaneous mutations takes place because of frame shift (removing of one particular piece of DNA) or due to bases under going tautomerism (keto forms get converted to enol, leading to false hydrogen bond formation). Induced mutations are induced by external agents. These will occur when DNA gets damaged or its repairing mechanism gets damaged. Induced mutations are induced by external agents. These will occur when DNA gets damaged or its repairing mechanism gets damaged. Reference: Microbiology by Presscott, Harley, Klein, 5th edition, McGraw Hill publishers, page no 246
K Rajakrishna's picture

Answer: 
Some mutations arise as natural errors in DNA replication (or as a result of unknown chemical reactions); these are known as spontaneous mutations. where as Mutations can also be caused by agents in the environment; these are induced mutations. Induced mutations increase the mutation rate over the spontaneous rate. reference: http://www.emunix.emich.edu/~rwinning/genetics/mutat.htm

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