What is the difference between Ex-vivo or In-vitro

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K Rajakrishna's picture

exvivo: Outside of the living body. Refers to a medical procedure in which an organ, cells, or tissue are taken from a living body for a treatment or procedure, and then returned to the living body.(1) invitro: A medical test, experiment, or procedure that is done outside of the body, such as in a test tube or laboratory dish.(2) the major difference is that exvivo involvle th use of tissues where as in vitro use of artificial medias which resemble the biological fluids. reference: 1)http://www.cancer.gov/dictionary/?CdrID=467838 2)http://lungcancer.about.com/od/glossary/g/invitro.htm (accessed on 25-01-2011)
Pushpendra Jain's picture

thnx sir

Mind Hunter; Jiyo aur Jine do

Dr Girija Sankar's picture

A)Ex-vivo and in-vitro are both done outside the animal models. However ex-vivo method involves removing an organ/cell from the body, maintaining the same physiological conditions and replacing the organ/cell in the body after the experimentation. Ref: http://www.cancer.gov/dictionary/?CdrID=467838 accessed on 24th Jan 2011 Whereas in-vitro conditions include testing the sample/product in the same physiological conditions as that of animal. Ref: http://www.medterms.com/script/main/art.asp?articlekey=4033 accessed on 24th Jan 2011.

Dr.G.Girija Sankar, Associate Professor Department of Pharmaceutical Biotechnology, College of Pharmaceutical Science, Andhra University.

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